{"id":1775,"date":"2026-08-28T03:00:20","date_gmt":"2026-08-28T03:00:20","guid":{"rendered":"https:\/\/luciuspharmacy.com\/product\/lucilemb\/"},"modified":"2026-08-30T03:53:27","modified_gmt":"2026-08-30T03:53:27","slug":"lucilemb","status":"publish","type":"product","link":"https:\/\/luciuspharmacy.com\/es\/product\/lucilemb\/","title":{"rendered":"LuciLemb"},"content":{"rendered":"<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">HIGHLIGHTS OF PRESCRIBING INFORMATION<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">These highlights do not include all the information needed to use LuciLemb safely and effectively. See full prescribing information for LuciLemb.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; color: rgb(88, 88, 88); font-size: 17px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 20px;\"><strong><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">INDICATIONS AND USAGE<\/span><\/strong><strong><\/strong><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">LuciLemb is an orexin receptor antagonist indicated for the treatment of adult patients with insomnia, characterized by difficulties with sleep onset and\/or sleep maintenance.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 20px;\"><strong><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">DOSAGE AND ADMINISTRATION<\/span><\/strong><strong><\/strong><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">\u2022<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;Recommended dose is 5 mg taken no more than once per night, immediately before going to bed, with at least 7 hours remaining before the planned time of awakening. Dosage may be increased to 10 mg based on clinical response and tolerability.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">\u2022<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;The maximum recommended dose is 10 mg once daily.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">\u2022<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;Time to sleep onset may be delayed if taken with or soon after a meal.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">\u2022<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;Hepatic Impairment:<\/span><\/p>\n<p style=\"text-indent: 28px; line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">o Moderate hepatic impairment: Initial and maximum recommended dosage is 5 mg no more than once per night.<\/span><\/p>\n<p style=\"text-indent: 28px; line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">o Severe hepatic impairment: Not recommended.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 20px;\"><strong><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">DOSAGE FORMS AND STRENGTHS<\/span><\/strong><strong><\/strong><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">Tablets:&nbsp;<\/span><span style=\"font-family: \u5b8b\u4f53;\">5<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;mg\u00d7<\/span><span style=\"font-family: \u5b8b\u4f53;\">30&nbsp;<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">tablets<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 20px;\"><strong><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">CONTRAINDICATIONS<\/span><\/strong><strong><\/strong><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">LuciLemb is contraindicated in patients with narcolepsy.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 20px;\"><strong><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">WARNINGS AND PRECAUTIONS<\/span><\/strong><strong><\/strong><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">\u2022<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;CNS Depressant Effects and Daytime Impairment: Impairs alertness and motor coordination including morning impairment. Risk increases with dose and use with other central nervous system (CNS) depressants. For patients taking LuciLemb 10 mg, caution against next-day driving and other activities requiring complete mental alertness.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">\u2022<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;Sleep Paralysis, Hypnagogic\/Hypnopompic Hallucinations, and Cataplexy-like Symptoms: May occur with use of LuciLemb.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">\u2022<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;Complex Sleep Behaviors: Behaviors including sleep-walking, sleepdriving, and engaging in other activities while not fully awake may occur. Discontinue immediately if a complex sleep behavior occurs.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">\u2022<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;Compromised Respiratory Function: Effect on respiratory function should be considered.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">\u2022<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;Worsening of Depression\/Suicidal Ideation: Worsening of depression or suicidal thinking may occur. Prescribe the lowest number of tablets feasible to avoid intentional overdosage.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">\u2022<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;Need to Evaluate for Co-morbid Diagnoses: Reevaluate if insomnia persists after 7 to 10 days of treatment.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 20px;\"><strong><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">ADVERSE REACTIONS<\/span><\/strong><strong><\/strong><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">The most common adverse reaction (reported in \u22655% of patients treated with&nbsp;<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">LuciLemb and at least twice the rate of placebo) was somnolence.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 20px;\"><strong><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">DRUG INTERACTIONS<\/span><\/strong><strong><\/strong><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">\u2022<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;Strong or moderate CYP3A inhibitors: Avoid concomitant use.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">\u2022<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;Weak CYP3A inhibitors: The maximum recommended dose is 5 mg.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: \u5b8b\u4f53; font-size: 14px;\">\u2022<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;Strong or moderate CYP3A inducers: Avoid concomitant use.<\/span><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">&nbsp;<\/span><\/p>\n<p style=\"line-height: 20px;\"><strong><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">Storage<\/span><\/strong><strong><\/strong><\/p>\n<p style=\"line-height: 20px;\"><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">Store at 20<\/span><span style=\"font-family: Symbol; font-size: 14px;\">\u00b0<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">C to 25<\/span><span style=\"font-family: Symbol; font-size: 14px;\">\u00b0<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">C (68<\/span><span style=\"font-family: Symbol; font-size: 14px;\">\u00b0<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">F to 77<\/span><span style=\"font-family: Symbol; font-size: 14px;\">\u00b0<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">F), excursions permitted between 15<\/span><span style=\"font-family: Symbol; font-size: 14px;\">\u00b0<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">C and 30<\/span><span style=\"font-family: Symbol; font-size: 14px;\">\u00b0<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">C (59<\/span><span style=\"font-family: Symbol; font-size: 14px;\">\u00b0<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">F and 86<\/span><span style=\"font-family: Symbol; font-size: 14px;\">\u00b0<\/span><span style=\"font-family: &quot;Times New Roman&quot;; font-size: 14px;\">F) [see USP Controlled Room Temperature]. Protect from moisture.&nbsp;<\/span><\/p>\n<p><\/p>\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>LuciLemb is an orexin receptor antagonist indicated for the treatment of adult patients with insomnia, characterized by difficulties with sleep onset and\/or sleep maintenance<\/p>","protected":false},"featured_media":1940,"comment_status":"open","ping_status":"closed","template":"","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"jetpack_seo_schema_type":""},"product_brand":[],"product_cat":[],"product_tag":[],"class_list":["post-1775","product","type-product","status-publish","has-post-thumbnail","first","instock","shipping-taxable","purchasable","product-type-simple"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/product\/1775","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/comments?post=1775"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/media\/1940"}],"wp:attachment":[{"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/media?parent=1775"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/product_brand?post=1775"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/product_cat?post=1775"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/product_tag?post=1775"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}