{"id":425,"date":"2026-04-12T08:59:08","date_gmt":"2026-04-12T08:59:08","guid":{"rendered":"https:\/\/luciuspharmacy.com\/?post_type=product&#038;p=425"},"modified":"2026-08-30T03:53:24","modified_gmt":"2026-08-30T03:53:24","slug":"lucielace-elacestrant-345-mgx30-tablets","status":"publish","type":"product","link":"https:\/\/luciuspharmacy.com\/es\/product\/lucielace-elacestrant-345-mgx30-tablets\/","title":{"rendered":"LuciElace 345mg"},"content":{"rendered":"<p><span style=\"color: rgb(89, 89, 89);\"><strong><span style=\"font-size:16px\">HIGHLIGHTS OF PRESCRIBING INFORMATION&nbsp;<\/span><\/strong><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);\"><strong><span style=\"font-size:16px\">These highlights do not include all the information needed to use LuciElace safely and effectively. See full prescribing information for LuciElace.<\/span><\/strong><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\"><br \/><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);\"><strong><span style=\"font-size:16px\">INDICATIONS AND USAGE<\/span><\/strong><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">LuciElace is an estrogen receptor antagonist indicated for:&nbsp;<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">\u2022 treatment of postmenopausal women or adult men, with ERpositive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy.<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\"><br \/><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);\"><strong><span style=\"font-size:16px\">DOSAGE AND ADMINISTRATION<\/span><\/strong><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">\u2022 Select patients for treatment with LuciElace based on the presence of ESR1 mutations.<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">\u2022 The recommended dosage of LuciElace is one 345 mg tablet taken orally, once daily, with food.<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">\u2022 Dose interruption, reduction, or permanent discontinuation may be required due to adverse reactions.&nbsp;<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\"><br \/><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);\"><strong><span style=\"font-size:16px\">DOSAGE FORMS AND STRENGTHS&nbsp;<\/span><\/strong><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">Tablets: 345 mg\u00d730 tablets<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\"><br \/><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);\"><strong><span style=\"font-size:16px\">CONTRAINDICATIONS&nbsp;<\/span><\/strong><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">None.<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\"><br \/><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);\"><strong><span style=\"font-size:16px\">WARNINGS AND PRECAUTIONS&nbsp;<\/span><\/strong><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">\u2022 Dyslipidemia: LuciElace may cause hypercholesterolemia and hypertriglyceridemia. Monitor lipid profile prior to starting treatment and periodically thereafter.<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">\u2022 Embryo-Fetal Toxicity: LuciElace can cause fetal harm. Advise of the potential risk to a fetus and to use effective contraception.&nbsp;<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\"><br \/><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);\"><strong><span style=\"font-size:16px\">ADVERSE REACTIONS&nbsp;<\/span><\/strong><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">The most common (&gt;10%) adverse reactions, including laboratory abnormalities, of LuciElace were musculoskeletal pain, nausea, increased cholesterol, increased AST, increased triglycerides, fatigue, decreased hemoglobin, vomiting, increased ALT, decreased sodium, increased creatinine, decreased appetite, diarrhea, headache, constipation, abdominal pain, hot flush, and dyspepsia.&nbsp;<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\"><br \/><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);\"><strong><span style=\"font-size:16px\">DRUG INTERACTIONS&nbsp;<\/span><\/strong><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">\u2022 Strong and Moderate CYP3A4 Inducers: Avoid concomitant use with LuciElace.<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">\u2022 Strong and Moderate CYP3A4 Inhibitors: Avoid concomitant use with LuciElace.<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\"><br \/><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);\"><strong><span style=\"font-size:16px\">USE IN SPECIFIC POPULATIONS&nbsp;<\/span><\/strong><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">\u2022 Lactation: Advise not to breastfeed.<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">\u2022 Hepatic impairment: Avoid use in patients with severe hepatic impairment (Child-Pugh C). Reduce the dosage for patients with moderate hepatic impairment (Child-Pugh B).&nbsp;<\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\"><br \/><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);\"><strong><span style=\"font-size:16px\">Storage&nbsp;<\/span><\/strong><\/span><\/p>\n<p><span style=\"color: rgb(89, 89, 89);font-size:16px\">Store at 20\u2103 to 25\u2103 (68\u2109 to 77\u2109), excursions permitted between 15\u2103 and 30\u2103 (59\u2109 and 86\u2109) [see USP Controlled Room Temperature]. Protect from moisture.&nbsp;<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>LuciElace is an estrogen receptor antagonist indicated for:  \u2022 treatment of postmenopausal women or adult men, with ERpositive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy.<\/p>","protected":false},"featured_media":2078,"comment_status":"open","ping_status":"closed","template":"","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"jetpack_seo_schema_type":""},"product_brand":[],"product_cat":[20],"product_tag":[],"class_list":["post-425","product","type-product","status-publish","has-post-thumbnail","product_cat-breast-cancer","first","instock","shipping-taxable","purchasable","product-type-simple"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/product\/425","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/comments?post=425"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/media\/2078"}],"wp:attachment":[{"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/media?parent=425"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/product_brand?post=425"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/product_cat?post=425"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/luciuspharmacy.com\/es\/wp-json\/wp\/v2\/product_tag?post=425"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}