{"id":511,"date":"2026-04-12T11:30:15","date_gmt":"2026-04-12T11:30:15","guid":{"rendered":"https:\/\/luciuspharmacy.com\/?post_type=product&p=511"},"modified":"2026-08-30T03:53:24","modified_gmt":"2026-08-30T03:53:24","slug":"lucipalbo-palbociclib-125-mgx21-capsules","status":"publish","type":"product","link":"https:\/\/luciuspharmacy.com\/pt\/product\/lucipalbo-palbociclib-125-mgx21-capsules\/","title":{"rendered":"LuciPalbo 125mg"},"content":{"rendered":"

HIGHLIGHTS OF PRESCRIBING INFORMATION <\/strong><\/span><\/p>\n

These highlights do not include all the information needed to use LuciPalbo safely and effectively. See full prescribing information for LuciPalbo.<\/strong><\/span><\/p>\n


<\/span><\/p>\n

INDICATIONS AND USAGE<\/strong><\/span><\/p>\n

LuciPalbo is a kinase inhibitor indicated for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in combination with: <\/span><\/p>\n

\u2022  an aromatase inhibitor as initial endocrine-based therapy in postmenopausal women or in men; or <\/span><\/p>\n

\u2022  fulvestrant in patients with disease progression following endocrine therapy. <\/span><\/p>\n


<\/strong><\/span><\/p>\n

DOSAGE AND ADMINISTRATION<\/strong> <\/span><\/p>\n

LuciPalbo capsules are taken orally with food in combination with an aromatase inhibitor or fulvestrant. <\/span><\/p>\n

\u2022  Recommended starting dose: 125 mg once daily taken with food for 21 days followed by 7 days off treatment.<\/span><\/p>\n

\u2022  Dosing interruption and\/or dose reductions are recommended based on individual safety and tolerability. <\/span><\/p>\n


<\/span><\/p>\n

DOSAGE FORMS AND STRENGTHS<\/strong> <\/span><\/p>\n

Capsules: 125mg\u00d721 Capsules.<\/span><\/p>\n


<\/span><\/p>\n

CONTRAINDICATIONS <\/strong><\/span><\/p>\n

None.<\/span><\/p>\n


<\/span><\/p>\n

WARNINGS AND PRECAUTIONS <\/strong><\/span><\/p>\n

\u2022  Neutropenia: Monitor complete blood count prior to start of LuciPalbo therapy and at the beginning of each cycle, as well as on Day 15 of the first 2 cycles, and as clinically indicated. <\/span><\/p>\n

\u2022  Embryo-Fetal Toxicity: LuciPalbo can cause fetal harm. Advise patients of potential risk to a fetus and to use effective contraception. <\/span><\/p>\n


<\/span><\/p>\n

ADVERSE REACTIONS <\/strong><\/span><\/p>\n

Most common adverse reactions (incidence \u226510%) were neutropenia, infections, leukopenia, fatigue, nausea, stomatitis, anemia, alopecia, diarrhea, thrombocytopenia, rash, vomiting, decreased appetite, asthenia, and pyrexia. <\/span><\/p>\n


<\/span><\/p>\n

DRUG INTERACTIONS <\/strong><\/span><\/p>\n

\u2022  CYP3A Inhibitors: Avoid concurrent use of LuciPalbo with strong CYP3A inhibitors. If the strong inhibitor cannot be avoided, reduce the LuciPalbo dose.<\/span><\/p>\n

\u2022  CYP3A Inducers: Avoid concurrent use of LuciPalbo with strong CYP3A inducers. <\/span><\/p>\n

\u2022  CYP3A Substrates: The dose of sensitive CYP3A4 substrates with narrow therapeutic indices may need to be reduced when given concurrently with LuciPalbo. <\/span><\/p>\n


<\/span><\/p>\n

USE IN SPECIFIC POPULATIONS <\/strong><\/span><\/p>\n

\u2022  Lactation: Advise not to breastfeed.<\/span><\/p>\n


<\/span><\/p>\n

Storage <\/strong><\/span><\/p>\n

Store at 20C to 25C (68F to 77F), excursions permitted between 15C and 30C (59F and 86F) [see USP Controlled Room Temperature]. Protect from moisture. <\/span><\/p>\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

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