{"id":595,"date":"2026-04-12T15:30:38","date_gmt":"2026-04-12T15:30:38","guid":{"rendered":"https:\/\/luciuspharmacy.com\/?post_type=product&p=595"},"modified":"2026-08-30T03:53:25","modified_gmt":"2026-08-30T03:53:25","slug":"lucipoma-pomalidomide-4-mgx21-capsules","status":"publish","type":"product","link":"https:\/\/luciuspharmacy.com\/pt\/product\/lucipoma-pomalidomide-4-mgx21-capsules\/","title":{"rendered":"LuciPoma 4mg"},"content":{"rendered":"

HIGHLIGHTS OF PRESCRIBING INFORMATION<\/strong><\/span><\/p>\n

These highlights do not include all the information needed to use LuciPoma safely and effectively. See full prescribing information for LuciPoma.<\/strong><\/span><\/p>\n

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INDICATIONS AND USAGE<\/strong><\/strong><\/span><\/p>\n

LuciPoma is a thalidomide analogue indicated, for the treatment of adult patients:<\/span><\/p>\n

\u2022 in combination with dexamethasone, for patients with multiple myeloma (MM) who have received at least two prior therapies including lenalidomide and a proteasome inhibitor and have demonstrated disease progression on or within 60 days of completion of the last therapy .<\/span><\/p>\n

\u2022 with AIDS-related Kaposi sarcoma (KS) after failure of highly active antiretroviral therapy (HAART) or in patients with KS who are HIV-negative. This indication is approved under accelerated approval based on overall response rate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s) .<\/span><\/p>\n

 <\/span><\/p>\n

DOSAGE AND ADMINISTRATION<\/strong><\/strong><\/span><\/p>\n

\u2022 MM: 4 mg per day taken orally on Days 1 through 21 of repeated 28-day cycles until disease progression .<\/span><\/p>\n

\u2022 KS: 5 mg per day taken orally on Days 1 through 21 of repeated 28-day cycles until disease progression or unacceptable toxicity.<\/span><\/p>\n

\u2022 Modify the dosage for certain patients with renal impairment or hepatic impairment.<\/span><\/p>\n

 <\/span><\/p>\n

DOSAGE FORMS AND STRENGTHS<\/strong><\/span><\/p>\n

Capsules: 4 mg\u00d721 capsules<\/span><\/p>\n

 <\/span><\/p>\n

CONTRAINDICATIONS<\/strong><\/strong><\/span><\/p>\n

\u2022 Pregnancy<\/span><\/p>\n

\u2022 Hypersensitivity<\/span><\/p>\n

 <\/span><\/p>\n

WARNINGS AND PRECAUTIONS<\/strong><\/strong><\/span><\/p>\n

\u2022 Increased Mortality: Observed in patients with MM when pembrolizumab was added to dexamethasone and a thalidomide analogue.<\/span><\/p>\n

\u2022 Hematologic Toxicity: Neutropenia was the most frequently reported Grade 3\/4 adverse event. Monitor patients for hematologic toxicities, especially neutropenia.<\/span><\/p>\n

\u2022 Hepatotoxicity: Hepatic failure including fatalities; monitor liver function tests monthly.<\/span><\/p>\n

\u2022 Severe Cutaneous Reactions: Discontinue LuciPoma (pomalidomide) for severe reactions.<\/span><\/p>\n

\u2022 Tumor Lysis Syndrome (TLS): Monitor patients at risk of TLS (i.e., those with high tumor burden) and take appropriate precautions.<\/span><\/p>\n

\u2022 Hypersensitivity: Monitor patients for potential hypersensitivity. Discontinue LuciPoma for angioedema and anaphylaxis.<\/span><\/p>\n

 <\/span><\/p>\n

ADVERSE REACTIONS<\/strong><\/strong><\/span><\/p>\n

\u2022 MM: Most common adverse reactions (\u226530%) included fatigue and asthenia, neutropenia, anemia, constipation, nausea, diarrhea, dyspnea, upper-respiratory tract infections, back pain, and pyrexia.<\/span><\/p>\n

\u2022 KS: Most common adverse reactions including laboratory abnormalities (\u226530%) are decreased absolute neutrophil count or white blood cells, elevated creatinine or glucose, rash, constipation, fatigue, decreased hemoglobin, platelets, phosphate, albumin, or calcium, increased ALT, nausea, and diarrhea.<\/span><\/p>\n

 <\/span><\/p>\n

DRUG INTERACTIONS<\/strong><\/strong><\/span><\/p>\n

Strong CYP1A2 Inhibitors: Avoid concomitant use of strong CYP1A2 inhibitors. If concomitant use of a strong CYP1A2 inhibitor is unavoidable, reduce LuciPoma dose to 2 mg.<\/span><\/p>\n

 <\/span><\/p>\n

USE IN SPECIFIC POPULATIONS<\/strong><\/strong><\/span><\/p>\n

\u2022 Lactation: Advise women not to breastfeed.<\/span><\/p>\n

 <\/span><\/p>\n

Storage<\/strong><\/strong><\/span><\/p>\n

Store at 20\u2103 to 25\u2103 (68\u2109 to 77\u2109), excursions permitted between 15\u2103 and 30\u2103 (59\u2109 and 86\u2109) [see USP Controlled Room Temperature]. Protect from moisture.<\/span><\/p>\n

<\/p>\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

LuciPoma is a thalidomide analogue indicated, for the treatment of adult patients: \u2022 in combination with dexamethasone, for patients with multiple myeloma (MM) who have received at least two prior therapies including lenalidomide and a proteasome inhibitor and have demonstrated disease progression on or within 60 days of completion of the last therapy. <\/p>","protected":false},"featured_media":1947,"comment_status":"open","ping_status":"closed","template":"","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"jetpack_seo_schema_type":""},"product_brand":[],"product_cat":[41],"product_tag":[],"class_list":["post-595","product","type-product","status-publish","has-post-thumbnail","product_cat-multiple-myeloma","first","instock","shipping-taxable","purchasable","product-type-simple"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/luciuspharmacy.com\/pt\/wp-json\/wp\/v2\/product\/595","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/luciuspharmacy.com\/pt\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/luciuspharmacy.com\/pt\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/luciuspharmacy.com\/pt\/wp-json\/wp\/v2\/comments?post=595"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/luciuspharmacy.com\/pt\/wp-json\/wp\/v2\/media\/1947"}],"wp:attachment":[{"href":"https:\/\/luciuspharmacy.com\/pt\/wp-json\/wp\/v2\/media?parent=595"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/luciuspharmacy.com\/pt\/wp-json\/wp\/v2\/product_brand?post=595"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/luciuspharmacy.com\/pt\/wp-json\/wp\/v2\/product_cat?post=595"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/luciuspharmacy.com\/pt\/wp-json\/wp\/v2\/product_tag?post=595"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}